Dr. Angelo’s academic background spans across the fields of physics, biochemistry, electrical engineering, and medicine. During his residency he became interested in developing novel methods for immunohistochemical multiplexing using mass spectrometry leading to the development of MIBI during his postdoctoral work in the Nolan lab at Stanford University. Dr. Angelo is now interested in optimizing MIBI and other mass reporter-based technologies further with the goal of identifying new transcriptional and translational signatures in solid tissue malignancies, and in allergic and other immunological disorders, that can be used to improve clinical diagnosis and treatment.

Dr. Bendall is an expert in protein biochemistry, mass spectrometry, and stem cell biology, and single cell analysis. His lab creates new methods for single cell proteomics that are applied to human stem cell biology, cancer immunology, and neurodegenerative disease.   These include his pioneering work in ICP-MS based flow cytometry (CyToF) for studying the regulation of the human hematopoietic immune system in health and disease as well as leveraging multiplexed ion beam imaging for human neuropathology.  His lab continually uses the collection of these tools for correlating single cell pathobiology with clinical outcomes in retrospective studies.