High-resolution multiplexed tissue imaging for quantitative spatial phenotype mapping of the tissue microenvironment
WITH MIBI TECHNOLOGY
Multiplexed Ion Beam Imaging (MIBI)
Multiplexed Ion Beam Imaging (MIBI™) technology from Ionpath enables high-definition spatial proteomics that uniquely provides actionable analysis of the tissue microenvironment—delivering novel insights into disease state, mechanism of action, and patient response.
MIBI provides rapid, robust, and high-resolution multiplexed tissue imaging of 40+ protein markers in a single scan. And when paired with sophisticated AI-powered analysis, quantitative spatial phenotyping of tissue microenvironments can be quickly and accurately achieved.
Comprehensive spatial analysis of the tissue microenvironment
Cell
Classification
- Identify and enumerate cell populations
- Visualize the tissue microenvironment
Protein
Quantification
- Quantify expression of checkpoints and other key proteins with spatial context
Spatial
Analysis
- Analyze interactions between target and effector cells
- Map tumor-immune boundaries
High-definition spatial proteomics that can inform therapeutic selection
High-definition spatial proteomics that can inform therapeutic selection
Achieve quantitative single-cell phenotype mapping at subcellular resolution and identify key mechanisms of action with clinical grade repeatability.
MIBIscope™ System
Highly multiplexed tissue imaging and analysis.
- Robust instrumentation
- Rigorously validated reagents
- Easy-to-use visualization software
Spatial Proteomic Services
MIBI-enabled phenotype mapping and insight generation.
- Quantitative cell segmentation, classification, and spatial analysis
- Responder, non-responder cohort comparisons
- Results with clinical-grade reproducibility
See published data on MIBI-share
Publications
MIBI Blog
News